Cleansers

Cleansers and supplements are available in the market but is the most effective colon cleanser? I'm thinking of taking cleaners or supplements along with vitamin C and calcium for stronger bones. I know I can't afford to get sick, not now or anytime soon. But what I'm worried about is the hubby. He looks sick because of the weight he gained in the past couple of months. I wish there's one tablet that would take away all his fats.